Socio-cultural perceptions that influence the choice of where to give birth among women in pastoralist communities of Afar region, Ethiopia:A qualitative study using the health belief model

Background: Facility-based delivery care provided by skilled birth attendants is globally considered to be crucial in reducing maternal mortality and morbidity. Although home deliveries are discouraged in Ethiopia due to an associated higher risk of maternal mortality or morbidity, the majority of women in the Afar region continue to deliver at home. Numerous barriers contribute to the low utilization of health facility delivery and skilled birth attendance services in the Afar region. Objective: Investigate the perceptions and decision-making processes of pastoralist women from Afar regarding home and institutional childbirth using the health belief model. Methods: A qualitative study was conducted to examine the socio-cultural perceptions that influence the decisionmaking of Afar women who utilize institutional delivery services and those who deliver at home. A total of 13 women aged 17 to 45 who gave birth within the past four years before the data collection period were selected, based on a purposive selection strategy, and took part in in-depth interviews. Atlas.ti 7 software was used for deductive content analysis. Upcoming themes were assigned to pre-determined constructs of the health belief model. Results: The main barriers to the demand, access and use of facility-based delivery were lack of awareness regarding the risks of childbirth; lack of support from social networks; the strong impact of husbands' opinions; difficulties associated with discussing reproductive health issues; the reliance on traditional birth attendants; lifestyle factors; cultural needs; and distrust in skilled birth attendants and health facilities. The factors that motivated women to use delivery services provided by skilled birth attendants were associated with strong communal and kinship support; antenatal care visits; high awareness of pregnancy-related risks; the influence of previous negative birth experiences; and the belief that facility-based delivery brings faster recovery from birthrelated wounds. Conclusions: The data give in-depth insights into a range of socio-cultural factors that prevent or facilitate the choice of institutional delivery. Based on our findings, recommendations to increase the uptake of institutional delivery services should focus on community and family involvement, as well as on individual factors. Similarly, effective integration of traditional birth attendants should be encouraged to advise mothers to utilize reproductive, maternal and neonatal health services, and arrange a timely referral of women to emergency obstetric care. Furthermore, making facility-based care more culturally attractive to the needs of pastoralist women should be addressed in future interventions

TB STIGMA – MEASUREMENT GUIDANCE

TB is the most deadly infectious disease in the world, and stigma continues to play a significant role in worsening the epidemic. Stigma and discrimination not only stop people from seeking care but also make it more difficult for those on treatment to continue, both of which make the disease more difficult to treat in the long-term and mean those infected are more likely to transmit the disease to those around them. TB Stigma – Measurement Guidance is a manual to help generate enough information about stigma issues to design and monitor and evaluate efforts to reduce TB stigma. It can help in planning TB stigma baseline measurements and monitoring trends to capture the outcomes of TB stigma reduction efforts. This manual is designed for health workers, professional or management staff, people who advocate for those with TB, and all who need to understand and respond to TB stigma

Extensive Genetic Diversity, Unique Population Structure and Evidence of Genetic Exchange in the Sexually Transmitted Parasite Trichomonas vaginalis

The human parasite Trichomonas vaginalis causes trichomoniasis, the world's most common non-viral sexually transmitted infection. Research on T. vaginalis genetic diversity has been limited by a lack of appropriate genotyping tools. To address this problem, we recently published a panel of T. vaginalis-specific genetic markers; here we use these markers to genotype isolates collected from ten regions around the globe. We detect high levels of genetic diversity, infer a two-type population structure, identify clinically relevant differences between the two types, and uncover evidence of genetic exchange in what was believed to be a clonal organism. Together, these results greatly improve our understanding of the population genetics of T. vaginalis and provide insights into the possibility of genetic exchange in the parasite, with implications for the epidemiology and control of the disease. By taking into account the existence of different types and their unique characteristics, we can improve understanding of the wide range of symptoms that patients manifest and better implement appropriate drug treatment. In addition, by recognizing the possibility of genetic exchange, we are more equipped to address the growing concern of drug resistance and the mechanisms by which it may spread within parasite populations

Mitochondrial physiology

As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

Socio-cultural perceptions that influence the choice of where to give birth among women in pastoralist communities of Afar region, Ethiopia: A qualitative study using the health belief model

Background: Facility-based delivery care provided by skilled birth attendants is globally considered to be crucial in reducing maternal mortality and morbidity. Although home deliveries are discouraged in Ethiopia due to an associated higher risk of maternal mortality or morbidity, the majority of women in the Afar region continue to deliver at home. Numerous barriers contribute to the low utilization of health facility delivery and skilled birth attendance services in the Afar region. Objective: Investigate the perceptions and decision-making processes of pastoralist women from Afar regarding home and institutional childbirth using the health belief model. Methods: A qualitative study was conducted to examine the socio-cultural perceptions that influence the decisionmaking of Afar women who utilize institutional delivery services and those who deliver at home. A total of 13 women aged 17 to 45 who gave birth within the past four years before the data collection period were selected, based on a purposive selection strategy, and took part in in-depth interviews. Atlas.ti 7 software was used for deductive content analysis. Upcoming themes were assigned to pre-determined constructs of the health belief model. Results: The main barriers to the demand, access and use of facility-based delivery were lack of awareness regarding the risks of childbirth; lack of support from social networks; the strong impact of husbands' opinions; difficulties associated with discussing reproductive health issues; the reliance on traditional birth attendants; lifestyle factors; cultural needs; and distrust in skilled birth attendants and health facilities. The factors that motivated women to use delivery services provided by skilled birth attendants were associated with strong communal and kinship support; antenatal care visits; high awareness of pregnancy-related risks; the influence of previous negative birth experiences; and the belief that facility-based delivery brings faster recovery from birthrelated wounds. Conclusions: The data give in-depth insights into a range of socio-cultural factors that prevent or facilitate the choice of institutional delivery. Based on our findings, recommendations to increase the uptake of institutional delivery services should focus on community and family involvement, as well as on individual factors. Similarly, effective integration of traditional birth attendants should be encouraged to advise mothers to utilize reproductive, maternal and neonatal health services, and arrange a timely referral of women to emergency obstetric care. Furthermore, making facility-based care more culturally attractive to the needs of pastoralist women should be addressed in future interventions

Operationalizing ecosystem services for the mitigation of soil threats: A proposed framework

Despite numerous research efforts over the last decades, integrating the concept of ecosystem services into land management decision-making continues to pose considerable challenges. Researchers have developed many different frameworks to operationalize the concept, but these are often specific to a certain issue and each has their own definitions and understandings of particular terms. Based on a comprehensive review of the current scientific debate, the EU FP7 project RECARE proposes an adapted framework for soil-related ecosystem services that is suited for practical application in the prevention and remediation of soil degradation across Europe. We have adapted existing frameworks by integrating components from soil science while attempting to introduce a consistent terminology that is understandable to a variety of stakeholders. RECARE aims to assess how soil threats and prevention and remediation measures affect ecosystem services. Changes in the natural capital's properties influence soil processes, which support the provision of ecosystem services. The benefits produced by these ecosystem services are explicitly or implicitly valued by individuals and society. This can influence decision- and policymaking at different scales, potentially leading to a societal response, such as improved land management. The proposed ecosystem services framework will be applied by the RECARE project in a transdisciplinary process. It will assist in singling out the most beneficial land management measures and in identifying trade-offs and win–win situations resulting from and impacted by European policies. The framework thus reflects the specific contributions soils make to ecosystem services and helps reveal changes in ecosystem services caused by soil management and policies impacting on soil. At the same time, the framework is simple and robust enough for practical application in assessing soil threats and their management with stakeholders at various levels